Instrumentation

Delivering excellent chemical synthesis

Our chemical lab is equipped with state-of-the-art safety fume hoods, rotary evaporators, safety cabinets for flammable/acid/toxic chemicals. We can perform air- and water-sensitive transformation thanks to argon-based Schlenk line technology, and leverage microwave irradiation for efficient cross-coupling reactions. We can work with reaction set-ups from sub-ml to 5L volumes, with both magnetic and overhead mechanical stirring.

      6                     >2600                            5

Fume hoods            Chemicals available             Dedicated instruments

Lab1
Lab2
Typical reaction setup

Waters Autopure Preparative HPLC

Preparative high performance liquid chromatography that enables the purification of 1–100 mg / injection. Equipped with evaporative light scattering (ELS), UV-vis, quadrupole QDa mass, photodiode array (PDA) detectors. Installs XBridge C18 and HILIC columns for broad polarity applicability, and nitrogen is supplied via Peak nitrogen generator. 

Preparative HPLC-MS is available to internal and external users via iLab

Waters Acquity UPLC

New generation analytical ultra-high performance liquid chromatography for analysis of reaction mixtures, quality control, and quantification. Equipped with SQ quadrupole MS detector and photodiode array (PDA) detector for detection of both UV-absorbing and non-absorbing analytes. Installs C18 and protein C4 BEH columns for broad polarity applicability. 

Analytical LC-MS is available to internal and external users via iLab

Shimadzu QP2020 NX GC-MS

Analytical gas chromatography for accurate detection and quantification of analytes. The instrument is equipped with single quadrupole mass detector with excellent robustness.

GC-MS is available to internal and external users via iLab

Teledyne CombiFlash Nextgen 300+ and RF+

State-of-the-art automated flash column chromatography systems equipped with UV-Vis detectors for reproducible and fast purification of organic compounds. Teledyne products allow flow rates of 1–300 mL/min and works with a variety of RediSep pre-packed columns.

Anton Paar Monowave 300 microwave reactor

Chemistry microwave reactor, enables homogeneous heating of small scale reactions (1–30 mL). Its 850 W magnetron can deliver up to 300 °C and 30 Bar. Ideal for transition metal-catalyzed and heterogeneous reactions. 

Agilent Cary 630 FT-IR spectrometer

This benchtop IR instrument based on attenuated total reflection (ATR) allows measurement of solids, powders, gums, and liquids with no sample preparation. Spectra can be acquired in less than a minute, and samples can be recovered.

FT-IR spectrometry is available to internal and external users. Please contact Peter Bellotti for more information.