Services

Chemical Synthesis

Tailor-made (multistep) syntheses of target compounds, creation of libraries and analogues. We can create molecules amenable to state-of-the-art bio-conjugation, from milligram to multi-decagram scale. Our experienced organic chemists leverage the whole reaction repertoire, modern organometallic chemistry, transition metal catalysis, and photocatalysis.

We are glad to discuss your synthetic needs!

Consulting

We develop synthetic strategies in synergy with our clients. Our chemists have extensive pharma and academic experience and will be glad to collaborate to create your chemical matter. We possess long-standing experience in writing chemistry sections for grant applications.

Contact us today tointegrate chemical synthesis in your research program.

Purification

We can purify an array of compounds via automated flash column chromatography (Teledyne, Combiflash) on silica, alumina, and ion exchange phases. We offer UPLC with C18 and HILIC columns on the Waters Autopure platform and we offer access to the instruments. We routinely perform recrystallization and vacuum distillation.

Keep in touch to devise together the optimal purification approach.

Analytical Services

We offer analytical services both in-house and through other Einstein’s shared facilities to identify, quantify, and characterize molecules. For more details, check 'Instrumentation' section.

  • NMR (1H, 13C, 19F, 31P, 2D experiments, etc.) (NMR core)

  • LC-MS (Waters Acquity)

  • GC-MS (Shimadzu)

  • FT-IR (Agilent) and melting point

  • Accurate mass spectrometry (MS Proteomics core)

 

Analysis, Publication

We provide thorough evaluation, analysis, and curation of experimental and analytical data. We provide publication-ready synthetic procedure, characterization, and supporting material for peer-reviewed publications. We support scientists en-route to IP protection of chemical matter.

Our commitment to excellence, our strive to enable scientific breakthroughs at Albert Einstein, and expertise ensures an data curation and publication follow-up.

 The first and second image are public domain, the third image is from Andra Mihali (CC BY-SA 2.0), the fourth image is from PNNL (CC BY-NC-SA 2.0), the fifth image is from Ryabitskii (CC BY 4.0).