1. I. Forzano and G. Santulli. Patent Foramen Ovale: The Unresolved Questions. Top Ital Sci J. 2024;1. https://doi.org/10.62684/dmfz6956; PMID:38585657.
2. V. Trimarco, R. Izzo, P. Gallo, M. V. Manzi, I. Forzano, D. Pacella, G. Santulli and B. Trimarco. Long-Lasting Control of LDL Cholesterol Induces a 40% Reduction in the Incidence of Cardiovascular Events: New Insights from a 7-Year Study. J Pharmacol Exp Ther. 2024;388:742-747. https://doi.org/10.1124/jpet.123.001878; PMID:37775305.
3. G. Santulli, V. Visco, F. Varzideh, G. Guerra, U. Kansakar, M. Gasperi, A. Marro, S. Wilson, M. N. V. Ferrante, A. Pansini, A. Pirone, F. Di Lorenzo, D. Tartaglia, G. Iaccarino, G. Macina, E. D. Agyapong, I. Forzano, S. S. Jankauskas, K. Komici, M. Ciccarelli and P. Mone. Prediabetes Increases the Risk of Frailty in Prefrail Older Adults With Hypertension: Beneficial Effects of Metformin. Hypertension. 2024;81:1637-1643. https://doi.org/10.1161/hypertensionaha.124.23087; PMID:38752357.
4. G. Santulli, V. Visco, M. Ciccarelli, M. N. V. Ferrante, P. De Masi, A. Pansini, N. Virtuoso, A. Pirone, G. Guerra, V. Verri, G. Macina, A. Taurino, K. Komici and P. Mone. Frail hypertensive older adults with prediabetes and chronic kidney disease: insights on organ damage and cognitive performance - preliminary results from the CARYATID study. Cardiovasc Diabetol. 2024;23:125. https://doi.org/10.1186/s12933-024-02218-x; PMID:38600564.
5. P. Mone, S. S. Jankauskas, M. V. Manzi, J. Gambardella, A. Coppola, U. Kansakar, R. Izzo, G. Fiorentino, A. Lombardi, F. Varzideh, D. Sorriento, B. Trimarco and G. Santulli. Endothelial Extracellular Vesicles Enriched in microRNA-34a Predict New-Onset Diabetes in Coronavirus Disease 2019 (COVID-19) Patients: Novel Insights for Long COVID Metabolic Sequelae. J Pharmacol Exp Ther. 2024;389:34-39. https://doi.org/10.1124/jpet.122.001253; PMID:38336381.
6. M. Lembo, V. Trimarco, R. Izzo, M. V. Manzi, F. Rozza, P. Gallo, C. Morisco, L. Bardi, G. Esposito, I. Forzano, G. Santulli and B. Trimarco. Achieving a Systolic Blood Pressure Below 130 mmHg Reduces the Incidence of Cardiovascular Events in Hypertensive Patients with Echocardiographic Left Ventricular Hypertrophy. J Pharmacol Exp Ther. 2024;390:4-10. https://doi.org/10.1124/jpet.123.001952; PMID:38135511.
7. V. Trimarco, M. V. Manzi, R. Izzo, P. Mone, M. Lembo, D. Pacella, G. Esposito, A. Falco, C. Morisco, P. Gallo, G. Santulli and B. Trimarco. The therapeutic concordance approach reduces adverse drug reactions in patients with resistant hypertension. Front Cardiovasc Med. 2023;10:1137706. https://doi.org/10.3389/fcvm.2023.1137706; PMID:37215551.
8. U. Kansakar, V. Trimarco, M. V. Manzi, E. Cervi, P. Mone and G. Santulli. Exploring the Therapeutic Potential of Bromelain: Applications, Benefits, and Mechanisms. Nutrients. 2024;16. https://doi.org/10.3390/nu16132060; PMID:38999808.
9. M. Ferrone, M. Ciccarelli, F. Varzideh, U. Kansakar, G. Guerra, F. A. Cerasuolo, A. Buonaiuto, A. Fiordelisi, E. Venga, M. Esposito, A. Rainone, R. Ricciardi, C. Del Giudice, F. Minicucci, T. Tesorio, V. Visco, G. Iaccarino, J. Gambardella, G. Santulli and P. Mone. Endothelial microRNAs in INOCA patients with diabetes mellitus. Cardiovasc Diabetol. 2024;23:268. https://doi.org/10.1186/s12933-024-02331-x; PMID:39039512.
10. R. Marfella, F. Prattichizzo, C. Sardu, P. Paolisso, N. D'Onofrio, L. Scisciola, R. La Grotta, C. Frigé, F. Ferraraccio, I. Panarese, M. Fanelli, P. Modugno, A. M. Calafiore, M. Melchionna, F. C. Sasso, F. Furbatto, D. D'Andrea, M. Siniscalchi, C. Mauro, A. Cesaro, P. Calabrò, G. Santulli, M. L. Balestrieri, E. Barbato, A. Ceriello and G. Paolisso. Evidence of an anti-inflammatory effect of PCSK9 inhibitors within the human atherosclerotic plaque. Atherosclerosis. 2023;378:117180. https://doi.org/10.1016/j.atherosclerosis.2023.06.971; PMID:37422356.
11. T. Tesorio, P. Mone, A. de Donato, V. Trimarco and G. Santulli. Linking lifestyle factors to cardiovascular risk through metabolomics: Insights from a large population of diabetic patients followed-up for 11 years. Atherosclerosis. 2023;367:37-39. https://doi.org/10.1016/j.atherosclerosis.2023.01.012; PMID:36725416.
12. P. Paolisso, L. Bergamaschi, F. Gragnano, E. Gallinoro, A. Cesaro, C. Sardu, N. Mileva, A. Foà, M. Armillotta, A. Sansonetti, S. Amicone, A. Impellizzeri, G. Esposito, N. Morici, O. J. Andrea, G. Casella, C. Mauro, D. Vassilev, N. Galie, G. Santulli, R. Marfella, P. Calabrò, E. Barbato and C. Pizzi. Reply to SGLT-2 inhibitors: Post-infarction interventional effects. Pharmacol Res. 2023;189:106664. https://doi.org/10.1016/j.phrs.2023.106664; PMID:36642618.
13. V. Trimarco, R. Izzo, P. Mone, M. Lembo, M. V. Manzi, D. Pacella, A. Falco, P. Gallo, G. Esposito, C. Morisco, G. Santulli and B. Trimarco. Therapeutic concordance improves blood pressure control in patients with resistant hypertension. Pharmacol Res. 2023;187:106557. https://doi.org/10.1016/j.phrs.2022.106557; PMID:36402254.
14. C. Sardu, G. Santulli, G. Savarese, M. C. Trotta, C. Sacra, M. Santamaria, M. Volpicelli, A. Ruocco, C. Mauro, G. Signoriello, L. Marfella, M. D'Amico, R. Marfella and G. Paolisso. Endothelial Dysfunction Drives CRTd Outcome at 1-Year Follow-Up: A Novel Role as Biomarker for miR-130a-5p. Int J Mol Sci. 2023;24. https://doi.org/10.3390/ijms24021510; PMID:36675028.
15. V. Trimarco, R. Izzo, A. Lombardi, A. Coppola, G. Fiorentino and G. Santulli. Beneficial effects of L-Arginine in patients hospitalized for COVID-19: New insights from a randomized clinical trial. Pharmacol Res. 2023;191:106702. https://doi.org/10.1016/j.phrs.2023.106702; PMID:36804278.
16. G. Santulli, F. Varzideh, I. Forzano, S. Wilson, L. Salemme, A. de Donato, A. Lombardi, A. Rainone, L. Nunziata, S. S. Jankauskas, T. Tesorio, G. Guerra, U. Kansakar and P. Mone. Functional and Clinical Importance of SGLT2-inhibitors in Frailty: From the Kidney to the Heart. Hypertension. 2023;80:1800-1809. https://doi.org/10.1161/hypertensionaha.123.20598; PMID:37403685.
17. G. Santulli, C. M. Pabelick, Y. K. Jan, P. Denise and C. de Lucia. Editorial: Methods and applications in clinical and translational physiology. Front Physiol. 2023;14:1169544. https://doi.org/10.3389/fphys.2023.1169544; PMID:37008021.
18. P. Paolisso, L. Bergamaschi, F. Gragnano, E. Gallinoro, A. Cesaro, C. Sardu, N. Mileva, A. Foà, M. Armillotta, A. Sansonetti, S. Amicone, A. Impellizzeri, G. Esposito, N. Morici, O. J. Andrea, G. Casella, C. Mauro, D. Vassilev, N. Galie, G. Santulli, R. Marfella, P. Calabrò, C. Pizzi and E. Barbato. Outcomes in diabetic patients treated with SGLT2-Inhibitors with acute myocardial infarction undergoing PCI: The SGLT2-I AMI PROTECT Registry. Pharmacol Res. 2023;187:106597. https://doi.org/10.1016/j.phrs.2022.106597; PMID:36470546.
19. G. Santulli. Non-Coding RNAs in Clinical Practice: From Biomarkers to Therapeutic Tools. J Pharmacol Exp Ther. 2023;384:225-226. https://doi.org/10.1124/jpet.122.001457; PMID:36581351.
20. G. Santulli. Cardiac Sarcoidosis: Updated Insights on Epidemiology and Diagnostic Criteria. Am J Cardiol. 2023;204:425-427. https://doi.org/10.1016/j.amjcard.2023.07.123; PMID:37599180. https://www.ncbi.nlm.nih.gov/pubmed/37599180
21. P. Mone, T. Tesorio, A. De Donato, A. Cioppa, S. S. Jankauskas, L. Salemme and G. Santulli. A novel urinary proteomic classifier predicts the risk of coronary artery disease. Eur J Prev Cardiol. 2023;30:1535-1536. https://doi.org/10.1093/eurjpc/zwad123; PMID:37075225.
22. P. Paolisso, L. Bergamaschi, A. Cesaro, E. Gallinoro, F. Gragnano, C. Sardu, N. Mileva, A. Foà, M. Armillotta, A. Sansonetti, S. Amicone, A. Impellizzeri, M. Belmonte, G. Esposito, N. Morici, J. Andrea Oreglia, G. Casella, C. Mauro, D. Vassilev, N. Galie, G. Santulli, P. Calabrò, E. Barbato, R. Marfella and C. Pizzi. Impact of SGLT2-inhibitors on contrast-induced acute kidney injury in diabetic patients with acute myocardial infarction with and without chronic kidney disease: Insight from SGLT2-I AMI PROTECT registry. Diabetes Res Clin Pract. 2023;202:110766. https://doi.org/10.1016/j.diabres.2023.110766; PMID:37276980.
23. P. Mone, G. Martinelli, A. Lucariello, A. L. Leo, A. Marro, S. De Gennaro, S. Marzocco, D. Moriello, S. Frullone, L. Cobellis and G. Santulli. Extended-release metformin improves cognitive impairment in frail older women with hypertension and diabetes: preliminary results from the LEOPARDESS Study. Cardiovasc Diabetol. 2023;22:94. https://doi.org/10.1186/s12933-023-01817-4; PMID:37085892.
24. Y. H. Kao, Y. J. Chen, S. Higa, N. Chattipakorn and G. Santulli. Editorial: Transcription factors and arrhythmogenesis. Front Physiol. 2023;14:1169747. https://doi.org/10.3389/fphys.2023.1169747; PMID:36926195.
25. P. Mone, A. Lombardi, L. Salemme, A. Cioppa, G. Popusoi, F. Varzideh, A. Pansini, S. S. Jankauskas, I. Forzano, R. Avvisato, X. Wang, T. Tesorio and G. Santulli. Stress Hyperglycemia Drives the Risk of Hospitalization for Chest Pain in Patients With Ischemia and Nonobstructive Coronary Arteries (INOCA). Diabetes Care. 2023;46:450-454. https://doi.org/10.2337/dc22-0783; PMID:36478189.
26. U. Kansakar, V. Trimarco, P. Mone, F. Varzideh, A. Lombardi and G. Santulli. Choline supplements: An update. Front Endocrinol (Lausanne). 2023;14:1148166. https://doi.org/10.3389/fendo.2023.1148166; PMID:36950691.
27. P. Mone, A. Lombardi, U. Kansakar, F. Varzideh, S. S. Jankauskas, A. Pansini, S. Marzocco, S. De Gennaro, M. Famiglietti, G. Macina, S. Frullone and G. Santulli. Empagliflozin Improves the MicroRNA Signature of Endothelial Dysfunction in Patients with Heart Failure with Preserved Ejection Fraction and Diabetes. J Pharmacol Exp Ther. 2023;384:116-122. https://doi.org/10.1124/jpet.121.001251; PMID:36549862.
28. J. Gambardella, U. Kansakar, C. Sardu, V. Messina, S. S. Jankauskas, R. Marfella, P. Maggi, X. Wang, P. Mone, G. Paolisso, D. Sorriento and G. Santulli. Exosomal miR-145 and miR-885 Regulate Thrombosis in COVID-19. J Pharmacol Exp Ther. 2023;384:109-115. https://doi.org/10.1124/jpet.122.001209; PMID:35772782.
29. P. Mone, U. Kansakar, A. Lucariello, A. Marro, A. Pansini, F. Varzideh, G. Nittolo, L. De Angelis, V. Trimarco, G. Martinelli, A. De Luca and G. Santulli. Choline Supplementation Improves Cognitive Performance in Frail Hypertensive Patients: Novel Insights on Endothelial Function from the INTERVENTIONIST Study. Eur J Prev Cardiol. 2023. https://doi.org/10.1093/eurjpc/zwad120; PMID:37070474.
30. S. S. Jankauskas, P. Mone, R. Avvisato, F. Varzideh, S. De Gennaro, L. Salemme, G. Macina, U. Kansakar, A. Cioppa, S. Frullone, J. Gambardella, M. Di Mauro, T. Tesorio and G. Santulli. miR-181c targets Parkin and SMAD7 in human cardiac fibroblasts: Validation of differential microRNA expression in patients with diabetes and heart failure with preserved ejection fraction. Mech Ageing Dev. 2023;212:111818. https://doi.org/10.1016/j.mad.2023.111818; PMID:37116731.
31. P. Mone, G. Guerra and G. Santulli. Complete or Culprit-Only PCI in Older Patients with MI. N Engl J Med. 2023;389:1923-1924. https://doi.org/10.1056/NEJMc2311551; PMID:37966296.
32. J. Gambardella, S. S. Jankauskas, U. Kansakar, F. Varzideh, R. Avvisato, N. Prevete, S. Sidoli, P. Mone, X. Wang, A. Lombardi and G. Santulli. Ketone Bodies Rescue Mitochondrial Dysfunction Via Epigenetic Remodeling. JACC Basic Transl Sci. 2023;8:1123-1137. https://doi.org/10.1016/j.jacbts.2023.03.014; PMID:37791311.
33. P. Mone, S. De Gennaro, D. Moriello, S. Frullone, R. D'Amelio, M. N. V. Ferrante, A. Marro and G. Santulli. Insulin resistance drives cognitive impairment in hypertensive pre-diabetic frail elders: the CENTENNIAL study. Eur J Prev Cardiol. 2023;30:1283-1288. https://doi.org/10.1093/eurjpc/zwad173; PMID:37196030.
34. R. Izzo, D. Pacella, V. Trimarco, M. V. Manzi, A. Lombardi, R. Piccinocchi, P. Gallo, G. Esposito, M. Lembo, G. Piccinocchi, C. Morisco, G. Santulli and B. Trimarco. Incidence of type 2 diabetes before and during the COVID-19 pandemic in Naples, Italy: a longitudinal cohort study. Lancet - eClinicalMedicine. 2023;66:102345. https://doi.org/10.1016/j.eclinm.2023.102345; PMID:38143804.
35. I. Forzano, S. Wilson, A. Lombardi, S. S. Jankauskas, U. Kansakar, P. Mone, F. Varzideh and G. Santulli. SGLT2 inhibitors: an evidence-based update on cardiovascular implications. Expert Opin Investig Drugs. 2023;32:839-847. https://doi.org/10.1080/13543784.2023.2263354; PMID:37740906.
36. J. Gambardella, A. Fiordelisi, D. Sorriento, F. Cerasuolo, A. Buonaiuto, R. Avvisato, A. Pisani, F. Varzideh, E. Riccio, G. Santulli and G. Iaccarino. Mitochondrial microRNAs Are Dysregulated in Patients with Fabry Disease. J Pharmacol Exp Ther. 2023;384:72-78. https://doi.org/10.1124/jpet.122.001250; PMID:35764328.
37. I. Forzano, R. Avvisato, F. Varzideh, S. S. Jankauskas, A. Cioppa, P. Mone, L. Salemme, U. Kansakar, T. Tesorio, V. Trimarco and G. Santulli. L-Arginine in diabetes: clinical and preclinical evidence. Cardiovasc Diabetol. 2023;22:89. https://doi.org/10.1186/s12933-023-01827-2; PMID:37072850.
38. R. Avvisato, I. Forzano, F. Varzideh, P. Mone and G. Santulli. A machine learning model identifies a functional connectome signature that predicts blood pressure levels: imaging insights from a large population of 35 882 patients. Cardiovasc Res. 2023;119:1458-1460. https://doi.org/10.1093/cvr/cvad065; PMID:37093975.
39. F. Varzideh, U. Kansakar, S. S. Jankauskas and G. Santulli. Aprocitentan: New insights. Front Cardiovasc Med. 2022;9:1093406. https://doi.org/10.3389/fcvm.2022.1093406; PMID:36620614.
40. S. Wilson, P. Mone, U. Kansakar, S. S. Jankauskas, K. Donkor, A. Adebayo, F. Varzideh, M. Eacobacci, J. Gambardella, A. Lombardi and G. Santulli. Diabetes and restenosis. Cardiovasc Diabetol. 2022;21:23. https://doi.org/10.1186/s12933-022-01460-5; PMID:35164744.
41. F. Varzideh, U. Kansakar, K. Donkor, S. Wilson, S. S. Jankauskas, P. Mone, X. Wang, A. Lombardi and G. Santulli. Cardiac Remodeling After Myocardial Infarction: Functional Contribution of microRNAs to Inflammation and Fibrosis. Front Cardiovasc Med. 2022;9:863238. https://doi.org/10.3389/fcvm.2022.863238; PMID:35498051.
42. V. Trimarco, R. Izzo, C. Morisco, P. Mone, M. Virginia Manzi, A. Falco, D. Pacella, P. Gallo, M. Lembo, G. Santulli and B. Trimarco. High HDL (High-Density Lipoprotein) Cholesterol Increases Cardiovascular Risk in Hypertensive Patients. Hypertension. 2022;79:2355-2363. https://doi.org/10.1161/hypertensionaha.122.19912; PMID:35968698.
43. G. Santulli, X. Wang and P. Mone. Updated ACC/AHA/HFSA 2022 guidelines on heart failure: what is new? From epidemiology to clinical management. Eur Heart J Cardiovasc Pharmacother. 2022;8:e23-e24. https://doi.org/10.1093/ehjcvp/pvac029; PMID:35460242.
44. F. Varzideh, S. S. Jankauskas, U. Kansakar, P. Mone, J. Gambardella and G. Santulli. Sortilin drives hypertension by modulating sphingolipid/ceramide homeostasis and by triggering oxidative stress. J Clin Invest. 2022;132. https://doi.org/10.1172/jci156624; PMID:35104807.
45. G. Santulli and P. Mone. In permanent AF with narrow QRS, AV junction ablation + CRT vs. rate-control drug therapy reduced mortality. Ann Intern Med. 2022;175:Jc21. https://doi.org/10.7326/j21-0016; PMID:35099986.
46. P. Paolisso, L. Bergamaschi, G. Santulli, E. Gallinoro, A. Cesaro, F. Gragnano, C. Sardu, N. Mileva, A. Foà, M. Armillotta, A. Sansonetti, S. Amicone, A. Impellizzeri, G. Casella, C. Mauro, D. Vassilev, R. Marfella, P. Calabrò, E. Barbato and C. Pizzi. Infarct size, inflammatory burden, and admission hyperglycemia in diabetic patients with acute myocardial infarction treated with SGLT2-inhibitors: a multicenter international registry. Cardiovasc Diabetol. 2022;21:77. https://doi.org/10.1186/s12933-022-01506-8; PMID:35570280.
47. A. Pansini, A. Lombardi, M. Morgante, S. Frullone, A. Marro, M. Rizzo, G. Martinelli, E. Boccalone, A. De Luca, G. Santulli and P. Mone. Hyperglycemia and Physical Impairment in Frail Hypertensive Older Adults. Front Endocrinol (Lausanne). 2022;13:831556. https://doi.org/10.3389/fendo.2022.831556; PMID:35498439.
48. P. Mone, F. Varzideh, U. Kansakar, C. Infante, A. Lombardi, A. de Donato, S. Frullone and G. Santulli. Omega-3 fatty acids coordinate glucose and lipid metabolism in diabetic patients. Lipids Health Dis. 2022;21:31. https://doi.org/10.1186/s12944-022-01642-w; PMID:35337345.
49. J. Gambardella, S. S. Jankauskas, S. L. D'Ascia, C. Sardu, A. Matarese, F. Minicucci, P. Mone and G. Santulli. Glycation of ryanodine receptor in circulating lymphocytes predicts the response to cardiac resynchronization therapy. J Heart Lung Transplant. 2022;41:438-441. https://doi.org/10.1016/j.healun.2021.12.008; PMID:35042640.
50. P. Mone, F. Varzideh, S. S. Jankauskas, A. Pansini, A. Lombardi, S. Frullone and G. Santulli. SGLT2 Inhibition via Empagliflozin Improves Endothelial Function and Reduces Mitochondrial Oxidative Stress: Insights From Frail Hypertensive and Diabetic Patients. Hypertension. 2022;79:1633-1643. https://doi.org/10.1161/hypertensionaha.122.19586; PMID:35703100.
51. P. Mone, B. Trimarco and G. Santulli. Aspirin, NOACs, warfarin: which is the best choice to tackle cognitive decline in elderly patients? Insights from the GIRAF and ASCEND-Dementia trials presented at the AHA 2021. Eur Heart J Cardiovasc Pharmacother. 2022;8:E7-e8. https://doi.org/10.1093/ehjcvp/pvab081; PMID:34849683.
52. R. Izzo, V. Trimarco, P. Mone, T. Aloè, M. Capra Marzani, A. Diana, G. Fazio, M. Mallardo, M. Maniscalco, G. Marazzi, N. Messina, S. Mininni, C. Mussi, G. Pelaia, A. Pennisi, P. Santus, F. Scarpelli, F. Tursi, A. Zanforlin, G. Santulli and B. Trimarco. Combining L-Arginine with vitamin C improves long-COVID symptoms: The LINCOLN Survey. Pharmacol Res. 2022;183:106360. https://doi.org/10.1016/j.phrs.2022.106360; PMID:35868478.
53. P. Mone, A. Pansini, F. Varzideh, A. de Donato, S. S. Jankauskas and G. Santulli. Exosome-Mediated Angiogenesis Underlies LVAD-Induced Bleeding in Patients With End-Stage Heart Failure. JACC Basic Transl Sci. 2022;7:262-264. https://doi.org/10.1016/j.jacbts.2022.01.011; PMID:35411327.
54. I. Forzano, F. Varzideh, R. Avvisato, S. S. Jankauskas, P. Mone and G. Santulli. Tirzepatide: A Systematic Update. Int J Mol Sci. 2022;23. https://doi.org/10.3390/ijms232314631; PMID:36498958.
55. P. Mone, A. Pansini, S. S. Jankauskas, F. Varzideh, U. Kansakar, A. Lombardi, V. Trimarco, S. Frullone and G. Santulli. L-Arginine Improves Cognitive Impairment in Hypertensive Frail Older Adults. Front Cardiovasc Med. 2022;9:868521. https://doi.org/10.3389/fcvm.2022.868521; PMID:35498050.
56. P. Mone, A. Pansini, S. Frullone, A. de Donato, V. Buonincontri, P. De Blasiis, A. Marro, M. Morgante, A. De Luca and G. Santulli. Physical decline and cognitive impairment in frail hypertensive elders during COVID-19. Eur J Intern Med. 2022;99:89-92. https://doi.org/10.1016/j.ejim.2022.03.012; PMID:35300886.
57. A. Cesaro, F. Gragnano, P. Paolisso, L. Bergamaschi, E. Gallinoro, C. Sardu, N. Mileva, A. Foà, M. Armillotta, A. Sansonetti, S. Amicone, A. Impellizzeri, G. Esposito, N. Morici, J. A. Oreglia, G. Casella, C. Mauro, D. Vassilev, N. Galie, G. Santulli, C. Pizzi, E. Barbato, P. Calabrò and R. Marfella. In-hospital arrhythmic burden reduction in diabetic patients with acute myocardial infarction treated with SGLT2-inhibitors: Insights from the SGLT2-I AMI PROTECT study. Front Cardiovasc Med. 2022;9:1012220. https://doi.org/10.3389/fcvm.2022.1012220; PMID:36237914.
58. P. Mone, A. Pansini, F. Calabrò, S. De Gennaro, M. Esposito, P. Rinaldi, A. Colin, F. Minicucci, A. Coppola, S. Frullone and G. Santulli. Global cognitive function correlates with P-wave dispersion in frail hypertensive older adults. J Clin Hypertens (Greenwich). 2022;24:638-643. https://doi.org/10.1111/jch.14439; PMID:35229449.
59. I. Forzano, P. Mone, F. Varzideh, S. S. Jankauskas, U. Kansakar, A. De Luca and G. Santulli. The selective aldosterone synthase inhibitor Baxdrostat significantly lowers blood pressure in patients with resistant hypertension. Front Endocrinol (Lausanne). 2022;13:1097968. https://doi.org/10.3389/fendo.2022.1097968; PMID:36568122.
60. P. Mone, R. Izzo, G. Marazzi, M. V. Manzi, P. Gallo, G. Campolongo, L. Cacciotti, D. Tartaglia, G. Caminiti, F. Varzideh, G. Santulli and V. Trimarco. L-Arginine Enhances the Effects of Cardiac Rehabilitation on Physical Performance: New Insights for Managing Cardiovascular Patients During the COVID-19 Pandemic. J Pharmacol Exp Ther. 2022;381:197-203. https://doi.org/10.1124/jpet.122.001149; PMID:35339987.
61. I. Forzano, P. Mone, G. Mottola, U. Kansakar, L. Salemme, A. De Luca, T. Tesorio, F. Varzideh and G. Santulli. Efficacy of the New Inotropic Agent Istaroxime in Acute Heart Failure. J Clin Med. 2022;11. https://doi.org/10.3390/jcm11247503; PMID:36556120.
62. P. Mone, J. Gambardella, A. Pansini, G. Martinelli, F. Minicucci, C. Mauro and G. Santulli. Cognitive dysfunction correlates with physical impairment in frail patients with acute myocardial infarction. Aging Clin Exp Res. 2022;34:49-53. https://doi.org/10.1007/s40520-021-01897-w; PMID:34101155.
63. H. Dridi, G. Santulli, J. Gambardella, S. S. Jankauskas, Q. Yuan, J. Yang, S. Reiken, X. Wang, A. Wronska, X. Liu, A. Lacampagne and A. R. Marks. IP3 receptor orchestrates maladaptive vascular responses in heart failure. J Clin Invest. 2022;132. https://doi.org/10.1172/jci152859; PMID:35166236.
64. P. Mone, J. Gambardella, A. Lombardi, A. Pansini, S. De Gennaro, A. L. Leo, M. Famiglietti, A. Marro, M. Morgante, S. Frullone, A. De Luca and G. Santulli. Correlation of physical and cognitive impairment in diabetic and hypertensive frail older adults. Cardiovasc Diabetol. 2022;21:10. https://doi.org/10.1186/s12933-021-01442-z; PMID:35045834.
65. C. Sardu, M. Massetti, N. Testa, L. D. Martino, G. Castellano, F. Turriziani, F. C. Sasso, M. Torella, M. De Feo, G. Santulli, G. Paolisso and R. Marfella. Effects of Sodium-Glucose Transporter 2 Inhibitors (SGLT2-I) in Patients With Ischemic Heart Disease (IHD) Treated by Coronary Artery Bypass Grafting via MiECC: Inflammatory Burden, and Clinical Outcomes at 5 Years of Follow-Up. Front Pharmacol. 2021;12:777083. https://doi.org/10.3389/fphar.2021.777083; PMID:34867407.
66. G. Santulli. In patients with early AF and CV conditions, early rhythm-control therapy vs. usual care reduced CV events at 5 years. Ann Intern Med. 2021;174:Jc6. https://doi.org/10.7326/acpj202101190-006; PMID:33395332.
67. P. Mone, J. Gambardella, A. Pansini, M. Rizzo, C. Mauro, F. Minicucci and G. Santulli. Impact of thrombus aspiration in frail STEMI patients. Aging Clin Exp Res. 2021;33:3081-3089. https://doi.org/10.1007/s40520-021-01848-5; PMID:33817772.
68. N. Renwick, A. El-Osta, I. Salamon, E. Broseghini, M. Ferracin, L. Poliseno, S. S. Jankauskas, G. Santulli, H. Xiao, P. K. T. Shiu, S. Roy and A. Goel. The Non-Coding RNA Journal Club: Highlights on Recent Papers-9. Noncoding RNA. 2021;7. https://doi.org/10.3390/ncrna7030058; PMID:34564320.
69. P. Mone, J. Gambardella, A. Pansini, A. de Donato, G. Martinelli, E. Boccalone, A. Matarese, S. Frullone and G. Santulli. Cognitive Impairment in Frail Hypertensive Elderly Patients: Role of Hyperglycemia. Cells. 2021;10. https://doi.org/10.3390/cells10082115; PMID:34440883.
70. S. S. Jankauskas, U. Kansakar, F. Varzideh, S. Wilson, P. Mone, A. Lombardi, J. Gambardella and G. Santulli. Heart failure in diabetes. Metabolism. 2021;125:154910. https://doi.org/10.1016/j.metabol.2021.154910; PMID:34627874.
71. P. Mone, J. Gambardella, F. Minicucci, A. Lombardi, C. Mauro and G. Santulli. Hyperglycemia Drives Stent Restenosis in STEMI Patients. Diabetes Care. 2021;44:e192-e193. https://doi.org/10.2337/dc21-0939; PMID:34531311.
72. S. S. Jankauskas, J. Gambardella, C. Sardu, A. Lombardi and G. Santulli. Functional Role of miR-155 in the Pathogenesis of Diabetes Mellitus and Its Complications. Noncoding RNA. 2021;7. https://doi.org/10.3390/ncrna7030039; PMID:34287359.
73. J. Gambardella, A. Fiordelisi, L. Spigno, L. Boldrini, G. Lungonelli, E. Di Vaia, G. Santulli, D. Sorriento, F. A. Cerasuolo, V. Trimarco and G. Iaccarino. Effects of Chronic Supplementation of L-Arginine on Physical Fitness in Water Polo Players. Oxid Med Cell Longev. 2021;2021:6684568. https://doi.org/10.1155/2021/6684568; PMID:33815657.
74. G. Fiorentino, A. Coppola, R. Izzo, A. Annunziata, M. Bernardo, A. Lombardi, V. Trimarco, G. Santulli and B. Trimarco. Effects of adding L-arginine orally to standard therapy in patients with COVID-19: A randomized, double-blind, placebo-controlled, parallel-group trial. Results of the first interim analysis. Lancet - eClinicalMedicine. 2021;40:101125. https://doi.org/10.1016/j.eclinm.2021.101125; PMID:34522871.
75. A. Adebayo, F. Varzideh, S. Wilson, J. Gambardella, M. Eacobacci, S. S. Jankauskas, K. Donkor, U. Kansakar, V. Trimarco, P. Mone, A. Lombardi and G. Santulli. l-Arginine and COVID-19: An Update. Nutrients. 2021;13. https://doi.org/10.3390/nu13113951; PMID:34836206.
76. C. Sardu, G. Santulli, G. Guerra, M. C. Trotta, M. Santamaria, C. Sacra, N. Testa, V. Ducceschi, G. Gatta, M. Amico, F. C. Sasso, G. Paolisso and R. Marfella. Modulation of SERCA in Patients with Persistent Atrial Fibrillation Treated by Epicardial Thoracoscopic Ablation: The CAMAF Study. J Clin Med. 2020;9. https://doi.org/10.3390/jcm9020544; PMID:32079238.
77. G. Santulli. In acute HF, intensive and sustained vasodilation did not reduce a composite of death or HF readmission at 180 days. Ann Intern Med. 2020;172:Jc54. https://doi.org/10.7326/acpj202005190-054; PMID:32422099.
78. C. Sardu, R. Marfella, P. Maggi, V. Messina, P. Cirillo, V. Codella, J. Gambardella, A. Sardu, G. Gatta, G. Santulli and G. Paolisso. Implications of AB0 blood group in hypertensive patients with covid-19. BMC Cardiovasc Disord. 2020;20:373. https://doi.org/10.1186/s12872-020-01658-z; PMID:32799852.
79. C. Sardu, J. Gambardella, M. B. Morelli, X. Wang, R. Marfella and G. Santulli. Hypertension, Thrombosis, Kidney Failure, and Diabetes: Is COVID-19 an Endothelial Disease? A Comprehensive Evaluation of Clinical and Basic Evidence. J Clin Med. 2020;9. https://doi.org/10.3390/jcm9051417; PMID:32403217.
80. M. B. Morelli, J. Gambardella, V. Castellanos, V. Trimarco and G. Santulli. Vitamin C and Cardiovascular Disease: An Update. Antioxidants. 2020;9. https://doi.org/10.3390/antiox9121227; PMID:33287462.
81. J. Gambardella, D. Sorriento, M. Bova, M. Rusciano, S. Loffredo, X. Wang, A. Petraroli, L. Carucci, I. Mormile, M. Oliveti, M. Bruno Morelli, A. Fiordelisi, G. Spadaro, P. Campiglia, M. Sala, B. Trimarco, G. Iaccarino, G. Santulli and M. Ciccarelli. Role of Endothelial G Protein-Coupled Receptor Kinase 2 in Angioedema. Hypertension. 2020;76:1625-1636. https://doi.org/10.1161/hypertensionaha.120.15130; PMID:32895019.
82. M. B. Morelli, C. Chavez and G. Santulli. Angiopoietin-like proteins as therapeutic targets for cardiovascular disease: focus on lipid disorders. Expert Opin Ther Targets. 2020;24:79-88. https://doi.org/10.1080/14728222.2020.1707806; PMID:31856617.
83. G. Santulli. Stroke prevention: Learning from the master (and COMMANDER). Sci Transl Med. 2018;10. https://doi.org/10.1126/scitranslmed.aav0340; PMID:31031885.
84. A. Kushnir, G. Santulli, S. R. Reiken, E. Coromilas, S. J. Godfrey, D. L. Brunjes, P. C. Colombo, M. Yuzefpolskaya, S. I. Sokol, R. N. Kitsis and A. R. Marks. Ryanodine Receptor Calcium Leak in Circulating B-Lymphocytes as a Biomarker in Heart Failure. Circulation. 2018;138:1144-1154. https://doi.org/10.1161/circulationaha.117.032703; PMID:29593014.
85. C. Sardu, G. Santulli, M. Santamaria, M. Barbieri, C. Sacra, P. Paolisso, F. D'Amico, N. Testa, I. Caporaso, G. Paolisso, R. Marfella and M. R. Rizzo. Effects of Alpha Lipoic Acid on Multiple Cytokines and Biomarkers and Recurrence of Atrial Fibrillation Within 1 Year of Catheter Ablation. Am J Cardiol. 2017;119:1382-1386. https://doi.org/10.1016/j.amjcard.2017.01.040; PMID:28258730.
86. M. Ciccarelli, R. Finelli, N. Rivera, G. Santulli, R. Izzo, N. De Luca, F. Rozza, M. Ceccarelli, S. Pagnotta, F. Uliano, R. Tremigliozzi, G. Condorelli, V. Trimarco and G. Iaccarino. The possible role of chromosome X variability in hypertensive familiarity. J Hum Hypertens. 2017;31:37-42. https://doi.org/10.1038/jhh.2016.9; PMID:26911533.
87. C. Sardu, M. Santamaria, M. R. Rizzo, M. Barbieri, M. di Marino, G. Paolisso, G. Santulli and R. Marfella. Telemonitoring in heart failure patients treated by cardiac resynchronisation therapy with defibrillator (CRT-D): the TELECART Study. Int J Clin Pract. 2016;70:569-76. https://doi.org/10.1111/ijcp.12823; PMID:27291327.
88. G. Santulli. Childhood obesity and education. Lancet Diabetes Endocrinol. 2016;4:957. https://doi.org/10.1016/s2213-8587(15)00517-3; PMID:26928651.
89. G. Santulli. Dietary Components and Metabolic Dysfunction: Translating Preclinical Studies into Clinical Practice. Nutrients. 2016;8. https://doi.org/10.3390/nu8100632; PMID:27754375.
90. G. Santulli, G. Pagano, C. Sardu, W. Xie, S. Reiken, S. L. D'Ascia, M. Cannone, N. Marziliano, B. Trimarco, T. A. Guise, A. Lacampagne and A. R. Marks. Calcium release channel RyR2 regulates insulin release and glucose homeostasis. J Clin Invest. 2015;125:1968-78. https://doi.org/10.1172/jci79273; PMID:25844899.
91. W. Xie, G. Santulli, S. R. Reiken, Q. Yuan, B. W. Osborne, B. X. Chen and A. R. Marks. Mitochondrial oxidative stress promotes atrial fibrillation. Sci Rep. 2015;5:11427. https://doi.org/10.1038/srep11427; PMID:26169582.
92. A. Wronska, I. Kurkowska-Jastrzebska and G. Santulli. Application of microRNAs in diagnosis and treatment of cardiovascular disease. Acta Physiol (Oxford). 2015;213:60-83. https://doi.org/10.1111/apha.12416; PMID:25362848.
93. G. Santulli. β-Blockers in diabetic patients with heart failure. JAMA Intern Med. 2015;175:657. https://doi.org/10.1001/jamainternmed.2014.8009; PMID:25844751.
94. G. L. Soares-Filho, S. Machado, O. Arias-Carrión, G. Santulli, C. T. Mesquita, F. Cosci, A. C. Silva and A. E. Nardi. Myocardial perfusion imaging study of CO(2)-induced panic attack. Am J Cardiol. 2014;113:384-8. https://doi.org/10.1016/j.amjcard.2013.09.035; PMID:24188891.
95. C. Sardu, R. Marfella, G. Santulli and G. Paolisso. Functional role of miRNA in cardiac resynchronization therapy. Pharmacogenomics. 2014;15:1159-68. https://doi.org/10.2217/pgs.14.76; PMID:25084208.
96. C. Sardu, R. Marfella and G. Santulli. Impact of diabetes mellitus on the clinical response to cardiac resynchronization therapy in elderly people. J Cardiovasc Transl Res. 2014;7:362-8. https://doi.org/10.1007/s12265-014-9545-9; PMID:24500410.
97. G. L. Soares-Filho, O. Arias-Carrión, G. Santulli, A. C. Silva, S. Machado, A. M. Valenca and A. E. Nardi. Chest pain, panic disorder and coronary artery disease: a systematic review. CNS Neurol Disord Drug Targets. 2014;13:992-1001. https://doi.org/10.2174/1871527313666140612141500; PMID:24923348.
98. C. Sardu, G. Carreras, S. Katsanos, V. Kamperidis, M. C. Pace, M. B. Passavanti, I. Fava, P. Paolisso, G. Pieretti, G. F. Nicoletti, G. Santulli, G. Paolisso and R. Marfella. Metabolic syndrome is associated with a poor outcome in patients affected by outflow tract premature ventricular contractions treated by catheter ablation. BMC Cardiovasc Disord. 2014;14:176. https://doi.org/10.1186/1471-2261-14-176; PMID:25480761.
99. G. Santulli, G. Iaccarino, N. De Luca, B. Trimarco and G. Condorelli. Atrial fibrillation and microRNAs. Front Physiol. 2014;5:15. https://doi.org/10.3389/fphys.2014.00015; PMID:24478726.
100. G. Santulli, B. Trimarco and G. Iaccarino. G-protein-coupled receptor kinase 2 and hypertension: molecular insights and pathophysiological mechanisms. High Blood Press Cardiovasc Prev. 2013;20:5-12. https://doi.org/10.1007/s40292-013-0001-8; PMID:23532739.
101. G. Santulli and H. Totary-Jain. Tailoring mTOR-based therapy: molecular evidence and clinical challenges. Pharmacogenomics. 2013;14:1517-26. https://doi.org/10.2217/pgs.13.143; PMID:24024901.
102. G. Santulli, S. D'Ascia, V. Marino and C. D'Ascia. Atrial function in patients undergoing CRT. JACC Cardiovasc Imaging. 2012;5:124-5; author reply 125. https://doi.org/10.1016/j.jcmg.2011.11.002; PMID:22239903.
103. G. Santulli, E. Cipolletta, D. Sorriento, C. Del Giudice, A. Anastasio, S. Monaco, A. S. Maione, G. Condorelli, A. Puca, B. Trimarco, M. Illario and G. Iaccarino. CaMK4 Gene Deletion Induces Hypertension. J Am Heart Assoc. 2012;1:e001081. https://doi.org/10.1161/jaha.112.001081; PMID:23130158.
104. G. Santulli. Coronary heart disease risk factors and mortality. JAMA. 2012;307:1137; author reply 1138. https://doi.org/10.1001/jama.2012.323; PMID:22436947.
105. G. Santulli. Thrombolysis outcomes in acute ischemic stroke patients with prior stroke and diabetes mellitus. Neurology. 2012;78:840. https://doi.org/10.1212/WNL.0b013e31824de51b; PMID:22411960.
106. S. L. D'Ascia, C. D'Ascia, V. Marino, A. Lombardi, R. Santulli, M. Chiariello and G. Santulli. Cardiac resynchronisation therapy response predicts occurrence of atrial fibrillation in non-ischaemic dilated cardiomyopathy. Int J Clin Pract. 2011;65:1149-55. https://doi.org/10.1111/j.1742-1241.2011.02732.x; PMID:21995693.
107. G. Santulli, A. Campanile, L. Spinelli, E. Assante di Panzillo, M. Ciccarelli, B. Trimarco and G. Iaccarino. G protein-coupled receptor kinase 2 in patients with acute myocardial infarction. Am J Cardiol. 2011;107:1125-30. https://doi.org/10.1016/j.amjcard.2010.12.006; PMID:21296320.
108. G. Galasso, G. Santulli, F. Piscione, R. De Rosa, V. Trimarco, R. Piccolo, S. Cassese, G. Iaccarino, B. Trimarco and M. Chiariello. The GPIIIA PlA2 polymorphism is associated with an increased risk of cardiovascular adverse events. BMC Cardiovasc Disord. 2010;10:41. https://doi.org/10.1186/1471-2261-10-41; PMID:20846430.
109. S. L. D'Ascia, G. Santulli, V. Liguori, V. Marino, C. Arturo, M. Chiariello and C. D'Ascia. Advanced algorithms can lead to electrocardiographic misinterpretations. Int J Cardiol. 2010;141:e34-6. https://doi.org/10.1016/j.ijcard.2008.11.144; PMID:19136171.
110. R. Izzo, E. Cipolletta, M. Ciccarelli, A. Campanile, G. Santulli, G. Palumbo, A. Vasta, S. Formisano, B. Trimarco and G. Iaccarino. Enhanced GRK2 expression and desensitization of betaAR vasodilatation in hypertensive patients. Clin Transl Sci. 2008;1:215-20. https://doi.org/10.1111/j.1752-8062.2008.00050.x; PMID:20443852.
111. F. Lanni, G. Santulli, R. Izzo, S. Rubattu, B. Zanda, M. Volpe, G. Iaccarino and B. Trimarco. The Pl(A1/A2) polymorphism of glycoprotein IIIa and cerebrovascular events in hypertension: increased risk of ischemic stroke in high-risk patients. J Hypertens. 2007;25:551-6. https://doi.org/10.1097/HJH.0b013e328013cd67; PMID:17278970.