Research

Cardiovascular Disease

We study the mechanisms underlying  major cardiovascular disorders, including heart failure, hypertension, and arrhythmias. We have identified new targets to treat these disorders and we are continuing to lead the way toward new discoveries.

 

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Metabolic Disorders

Our lab is studying the key mechanisms underlying diabetes mellitus, with a special focus on pancreatic beta cell dysfunction.

  

 

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Non-coding RNA

We investigate the functional contribution of non-coding RNAs (including microRNAs) to the pathophysiology of human disease. We are studying non-coding RNAs both as biomarkers and therapeutic targets.

 

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Calcium

The Santulli's Lab is investigating the functional roles of calcium in health and disease in various tissues and cell types.

 

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Stem Cells

We are investigating the mechanisms to obtain mature human stem cells and how to apply stem cells in human disease. To this aim, we are applying top-notch bioengineering approaches.

 

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Translational Medicine

We are applying our fundamental discoveries to the clinical scenario, with the ultimate goal of improving human health.

Bioinformatics 

 

Aging and Healthy Longevity

Our Lab is investigating the physiology and biology of aging and the mechanisms underlying senescence.

We also study the roles of diet and nutrition in healthy longevity.