Research
Cardiovascular Disease
We study the mechanisms underlying major cardiovascular disorders, including heart failure, hypertension, and arrhythmias. We have identified new targets to treat these disorders and we are continuing to lead the way toward new discoveries.
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Metabolic Disorders
Our lab is studying the key mechanisms underlying diabetes mellitus, with a special focus on pancreatic beta cell dysfunction.
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Non-coding RNA
We investigate the functional contribution of non-coding RNAs (including microRNAs) to the pathophysiology of human disease. We are studying non-coding RNAs both as biomarkers and therapeutic targets.
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Calcium
The Santulli's Lab is investigating the functional roles of calcium in health and disease in various tissues and cell types.
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Stem Cells
We are investigating the mechanisms to obtain mature human stem cells and how to apply stem cells in human disease. To this aim, we are applying top-notch bioengineering approaches.
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Translational Medicine
We are applying our fundamental discoveries to the clinical scenario, with the ultimate goal of improving human health.
Aging and Healthy Longevity
Our Lab is investigating the physiology and biology of aging and the mechanisms underlying senescence.
We also study the roles of diet and nutrition in healthy longevity.
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Clinical Research
We perform clinical research in the fields of cardiovascular medicine, diabetes, and aging.
Please find here our clinical publications.